The short-staffed Hokies (18-4, 7-3 ACC) drop their first game in Cassell Coliseum, falling 72-64 to Louisville.
The Cardinals downed the Hokies at the Cassell, 75-68.
Virginia Tech solidified their tournament resume with two wins.
The Hokies, sitting at 27-3 over their last 30 games at home, look to make it 29-3.
Hokies have 19 turnovers as they lose a winnable game and fall to 13-5 (2-3 ACC).
An offensive explosion led by Seth Allen comes up short against the #8 Cardinals.
Barrage of Cardinals' three-pointers leads to the Hokies' third consecutive loss.
Virginia Tech men's basketball dropped the first of a four-game stretch against ranked ACC opponents.