That time of year again - Fantasy Football advice needed

Hello fellow Hokies. Its that time again where I imagine a lot of us are have upcoming fantasy drafts, so wanted to start a thread to discuss advice for the upcoming season.

For myself specifically, the $100 league I am in drafts next weekend, and through random order I end up having the first pick.

Looking for some input on who I should be taking off the board at #1. Some info about the league itself:

10 team league, PPR, roster starts:
QB
QB
WR
WR
WR
RB
RB
TE
FLEX RB/RB/TE
K
DEF

Passing TDs worth 6 as well, so premium on having good QBs and with 3 starting WRs need to have really 2 good ones to compete.

I was thinking Antonio Brown first given this, but would love to get thoughts from some other fantasy fanatics.

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Taylor, looking desperately throws it deep..HAS A MAN OPEN DANNY COALE WITH A CATCH ALL THE WAY DOWN TO THE FIVE!!!!....hes still open

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Now finish up them taters; I'm gonna go fondle my sweaters.

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Another white bronco? The first one didn't go too far.

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Yes,that's the Hokie Bird riding a camel. Why'd you ask?